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SUMMARY OF GRANTS

Since its inception through September 30, 2020, the Foundation has awarded over $2,500,000 in grants to 69 recipients.

GRANT TITLE INSTITUTION COUNTRY LEAD RESEARCHER TOTAL ($)
2020 Burst suppression with Propofol for seizure control post-cardiac arrest University of California United States Edilberto Amorin, MD $765,317
Assessing synaptic density in cardiac arrest survivors using [11C]UCB-J PET: a pilot study Yale New Haven Hospital United States Rachel Beekman, MD
A novel approach to bradycardia during pre-term neonatal resuscitation using an ovine model of asphyxia University at Buffalo United States Praveen Chandrasekaran, MD, MS
Time for a change: use of Doppler ultrasound for checking pulses in cardiac arrest Feinstein Institutes for Medical Research United States Allison Cohen, MD
Using unstructured clinical data to predict critical illness University of Pittsburgh United States Adam Frisch, MD
CPR-REBOA: improving outcome of prehospital cardiopulmonary resuscitation with balloon occlusion of the descending aorta University Hospital Bern Switzerland Anja Levis, MD
Derivation and validation of a clinical decision rule for the early prediction of shock-refractory VT/VF out-of-hospital cardiac arrest Oregon Health and Science University United States Joshua Lupton, MD
Mitochondrial injury differs with age in rat model Soochow University China Yan Xiao, MD
Bioadhesive Paste for Instant Hemorrhage Control of Vascular and Solid Organ Injuries Mayo Clinic United States Christoph Nabzdyk, MD
Dodecafluoropentane to Reduce Ischemic-Reperfusion Injury in a Swine Model of Cardiac Arrest University of Florida United States Travis Murphy, MD
Evaluating Neuroprotective Therapies that Modulate Leukocyte Infiltration into the Brain Following Cardiac Arrest and Resuscitation University of Pittsburgh United States Tanner Smida, NREMT-B
Humanizing the Intensive Care Unit (ICU): Perspectives of patients and their families on the use of the Get to Know Me board Mayo Clinic United States Sumera Ahmad, MBBS
Mitochondrial dynamics as target for inhaled argon therapy after cardiac arrest Istituto di Ricerche Farmacoogiche Mario Negri Italy Francesca Fumagalli, PhD
Increased Mitochondrial-Mediated Survival with Improved Neurological Recovery after Metformin Treatment for Brain Injury after Cardiac Arrest Feinstein Institutes for Medicine, Northwell Health United States Rishabh Choudhary, PhD
Methylene blue for treatment of cardiac arrest Aarhus University Hospital Denmark Lauge Vammen, MD
Using Machine Learning Algorithms to Predict Critical Care Outcomes from Emergency Department Triage Data University of Pittsburgh United States Stephanie Frisch, PhD
Effects of sedation on post-cardiac arrest neurological recovery Massachusetts General Hospital United States Takamitsu Ikeda, MD
Multidisciplinary Implementation of Inspiratory Muscle Training for Mechanically Ventilated Patients: A Feasibility Study Mayo Clinic United States Heyi Li, MD
CAMeLOT study: Cardiac Arrest Prediction by Machine Learning to Improve Outcome in Tots University of Texas Southwestern Medical Center United States Priscilla Yu, MD
Impaired organ repair after sepsis: role of tissue resident macrophages and recruited monocytes (ORISMO) INSERM France Charles de Roquetaillade, MD
Augmented Reality - Cardiopulmonary Resuscitation (AR-CPR) Interactive Handbook: A FeasibilityStudy of Augmented Reality Basic Life Support Training for Malaysia Public Users Universiti Teknologi Mara Malaysia Malaysia Mohd Fazrul Mokhtar, MD
Aloud Real-time Reading of ICU Diaries for Prevention of Negative Post-ICU Psychological Outcomes: A Feasibility Study Mayo Clinic United States Kimberly Johnson, MD
Delivery Room Peak Performance for Neonates with Congenital Anomalies Children's Hospital of Philadelphia United States Heidi Herrick, MD
2019 Investigate the effects of WIN55, 212-2 on CB2 receptors following cardiopulmonary resuscitation Virginia Commonwealth University United States Jennifer Bradley, MS, CRA $676,368
Compare personalized selection of an optimal MAP to each patient versus standard hemodynamic management with all having same BP goal University of Pittsburgh School of Medicine United States Patrick Coppler, PA-C
Aim to improve initial & long-term survival & diminish neurological damage after global ischemia & reperfusion by administration of Hemarina-M101 after CA Inselspital Bern University Hospital Switzerland Michael Glas, Dr. Medicine
Hypothesize that CPR augmented by balloon aortic occlusion benefits from adaptive balloon-wealing protocol tailored to maintain a blood pressure Travis Air Force Base, Clinical Investigation Facility United States Guillaume Hoareau, DVM, PhD
Will test the prognostic potential of LPC using an established rate model of cardiac arrest and human patients Feinstein Institute for Medical Reaserch United States Junhwan Kim, PhD
Effect of MAP on cerebral perfusion & metabolism after CA in porcine Oslo University Hospital Norway Christina Skare, MD
Improving simulation-based medical education in pediatric resuscitation: Real-time feedback and visual attention Medical University of Vienna United States Michael Wagner, MD
Test the feasibility and yield of nanopore sequencing, as compared to culture, for assessment of body fluid speciments from post Cardiac Arrest patients Univerisity of Pittsburgh United States Alexandra Weissman, MD
Mechanisms ot pharmacological hypothermia induced by cannabinoid receptor agonist WIN55, 212-2 on outcomes of CPR Soochow University Second Affiliated Hospital (Research at Virginia Commonwealth University) China (United States) Yan Xiao, MD
Amplitude spectral area to assess hemodynamic and metabolic interventions during cardiac arrest Rosalind Franklin University of Medicine & Science United States Salvatore Aiello, MD, PhD Student
Intensive care knowledge translation in practice (ICU knowledge-TIP) University Clinical Center of Republika Srpska Bosnia and Herzegovina Pedja Kovacevic, MD, PhD
Targeting heme oxygenase-1 with H2 gas inhalation to improve cardiac arrest outcomes The Feinstein Institutes for Medical Research United States Kei Hayashida, MD, PhD
Mitigation of ischemia-reperfusion injury and cardiovascular collapse during resuscitative endovascular balloon occlusion of the aorta in trauma using adenosine, lidocaine, and magnesium Madigan Army Medical Center United States Daniel Lammers, MD
Endothelial dysfunction and repair during septic shock: transcriptome analysis of circulating endothelial cells and blood outgrowth endothelial cells by RNA-seq INSERM U976 France Stéphanie Pons, MD
Level of soluble CD73 association with outcome, and predictive utility for post-cardiac arrest cerebral edema Maine Medical Center United States Jonathan Rud, DO, PhD
Sex hormone differences in cardiac arrest patients University of Illinois at Chicago United States Pavitra Kotini-Shah, MD
Improving successful defibrillation of ventricular fibrillation in a porcine model of cardiac arrest using machine learning algorithms with physiology guided resuscitation Li Ka Shing Knowledge Institute Canada Rohit Mohindra, MD
Testing the impact of intra-shift naps during night shifts on blood pressure dipping and heart rate variability among EMS clinicians University of Pittsburgh United States Lenny Weiss, MD
2018 Test hypothesis that rapidly induced therapeutic hypothermia in those with acute coronary occlusion extends the door to perfusion time from 120 to 240 minutes with no increase in myocardial infarct size. University of Arizona United States Madhan Shanmugasundaram, MD $706,057
Determining the impact of telemedicine on outcomes after pediatric out-of-hospital cardiac arrest Avera McKenna Hospital United States Katie A. DeJong, DO
Role of electrical impedance in pseudo pulseless electrical activity Dartmouth Hitchcock Medical Center United States Alexander Lindqwister, MD Candidate
The usage and effects of epinephrine in pseudo-PEA University of Pennsylvania United States Felipe Teran-Merino, MD
Impact of kynurenin pathway (KP) inhibition on survival and neurological outcome after cardiac arrest and CPR Istituto di Ricerche Farmacologiche Mario Negri Italy Aurora Magliocca, MD
Define subsets of pulseless electrical activity (PEA) following initial out-of-hospital cardiac rhythm analysis using machine learning University of Pennsylvania United States Steven Balian, MD
Advance healthcare provider resuscitation quality using an immersive augmented reality CPR training system University of Pennsylvania United States Marion Leary, MD
Mechanisms of coagulation following OHCA and how influenced by post arrest care including therapeutic hypothermia. Yeouido St. Mary’s Hospital, Seoul Korea Jeong Ho Park, MD, PhD
Testing hypothesis that shock burden will intensify myocardial injury Rosalind Franklin University of Medicine and Science United States Salvatore Aiello, MS
Feasiblity of random allocation to active RIC vs. Sham RIC quickly upon ED arrival following resuscitation University of Washington United States Emily Bartlett, MD
Investigate the pharmacokinetics of ART-123 in healthy pigs to verify that the relatively prolonged circulation times seen in other species will be reproduced in swine. University of Michigan United States Colin Greineder, MD
Determine potential neuroprotective effects of dexmedetomidine Massachusetts General Hospital, Simches Research Center United States Michael Silverman, MD
Rapid Cycle Deliberate Practice in First Five Minutes Training to Improve Team Dynamics and Resuscitation Skills Northeast Ohio Medical University United States Wendy Van Ittersum, MD
Determine whether systemic allogeneic CDC administration reduces myocardial and neurological injury in swine with post-cardiac arrest syndrome. University of Buffalo United States Brian Weil, PhD
Investigate whether the three second pause in compressions is long enough to provide two ventilations when using mechanical chest compressions during out-of-hospital cardiac arrest Amsterdam University Medical Center Netherlands Hans van Schuppen, M.D.
Establish the effectiveness of physiologically guided resuscitation by use of NIRS during CPR Kyoto University Health Service Japan Takeyuki Kiguchi, M.D.
2017 Investigation of organ dysfunction of diabetics following cardiac arrest Aarhus University Hospital Denmark Lauge Vammen, MD $193,525
The study of adrenaline and its effects on cardiac arrest St. Michael’s University Canada Steve Lin, MD
Use eye-tracking technology to characterize how providers focus their visual attention during newborn resuscitation and assess the impact of a novel resuscitation monitor University of Pennsylvania United States Elizabeth E. Foglia, MD
Study involving cardiogenic shock patients randomized to therapeutic hypothermia plus standard medical care or standard medical care alone University of Chicago Medicine United States Jonathan Paul, MD
Test use of Coenzyme Q10 for neuroprotection in post-cardiac arrest patients to mitigate mitochondrial injury Aarhus University Hospital Denmark Mathias Holmberg, MD
A scoping review of existing studies investigating OHCA in the Arab Gulf Region Fanshawe College Canada Alan M. Batt, MICP
2014‑2016 Implementation of a multicenter registry for pediatric ED resuscitations using video recording University of Pennsylvania United States Aaron Donoghue, MD $130,681
Development of multimodal monitoring and treatment protocols for high-risk post-arrest patients University of Pittsburgh United States Jonathan Elmer, MD
Optimizing public access defibrillation deployment incorporating hours of operation University of Toronto Canada Timothy Chan, PhD
Test hypothesis that therapeutic hypothermia will be anti-arrhythmic during resuscitation and improve ROSC after VF arrest Case Western Reserve University United States Joseph Stephen Piktel, MD
To investigate temporal differences between asphyxial induced cardiac arrest (ACA) and ventricular fibrillation induced cardiac arrest (VFCA) and its impact on myocardial and neurological injury; to examine the temporal changes in brain and cardiac ATP levels, antioxidant reserve, and the generation of reactive oxygen species Aarhus University Hospital Denmark Soren Rahbek, MD
Potassium cardioplegia with calcium reversal for ventricular fibrillation arrest: a blinded randomized controlled trial University of Pittsburgh United States Keith Marrill, MD